Section I: Telomerases, Telomeres and Cancer. Section Ia: Telomerase Activity and Cancer. 1. The Significance of Quantitative Evaluation of Telomerase Activity and hTERT mRNA Expression in Colorectal Cancers; M. Pogessi, et al. 2. The Role of Telomerase De-Regulation in Keratinocyte Immortality and the Progression of Human Head and Neck Cancer; E.K. Parkinson. 3. Telomerase in Mesothelioma: Diagnostic and Therapeutic Applications; K. Dhaene. 4. Telomerase Activity in Mesenchymal Tumors; R. Schneider-Stock, et al. 5. Telomerase Activity in Neuroblastomas: A New Molecular Marker for Treatment Stratification and Prognostic Grouping; C. Poremba, B. Dockhorn-Dworniczak. 5. Telomerase and Radiosensiticity of Human Tumors; T.K. Pandita. 7. Amplification of hTERT, the Telomerase Reverse Transcriptase Gene in Human Cancers; D. Xu, et al. 8. Telomerase Activity as a Marker of Tumor Cell Survival to Evaluate Sensitivity of Neoplastic Cells to Cancer Treatment; I. Faraoni, E. Bonmassar. 9. PNA and Oligonucleotide Inhibitors of Human Telomerase; G. Gavory, S. Balasubramanian. 10. Potential of the Telomerase Catalytic Subunits as a Universal Tumor-Associated Antigen for Cancer Immunotherapy; R.H. Vonderheide, W.C. Hahn. Section II: Structure and Function of Telomerase and Telomeres. Section IIa: Humans. 11. The Making of Telomerases; J. Lingner, C. Wenz. 12. Regulation of Telomerase Activity; J.-P. Liu, et al. 13. Telomeres and Mechanisms of DNA Double Strand Break Repair; P. Slijepcevic. 14. Roles for hTERT and Telomerase in Cell Differentiation and Apoptosis; M.P. Mattson, et al. Section IIb: Ciliates, Yeasts and other Eukaryotes. 15. Human, Mouse and Yeast Telomerase; T.J. Moriarty, C. Autexier. 16. The Biology of Telomeres in Hypotrichous Ciliates* 17. DNA Primer Extension by Telomerase; H. Manor, et al. 18. Yeast Telomerases: Structure, Mechanisms and Regulation; N.F. Lue. 19. RAP1 Binding and Length Regulation of Yeast Telomeres; J. Wahlin, M. Cohn. 20. Linear Plasmids in Yeasts and Filamentous Fungi; L. Civitelli, F. Ascenzioni. 21. New Telomere Formation During the Process of Chromatin Diminution in the Parasitic Nematodes Ascaris suum and Parascaris univalens; F. Muller. 22. Telomerase Activity in Sponges (Porifera), the Closest Related Taxa of the Hypothetical Ancestral Animal the Urmetazoa; W.E.G. Muller. 23. Structure and Maintenance of Chromosome Ends in Plants; J. Fajkus, U. Zentgraf. Section III: Maintaining Telomeres without Telomrase. 24. Telomeres without Telomerase in Saccharomyces cerevisiae; E.J. Louis. 25. Recombinational Telomere Elongation in the Yeast Kluyveromyces lactis; M.J. McEachern. 26. Telomere Maintanance in Human Cell Lines and Tumors without Telomerase; C.L. Fasching, R.R. Reddel. Section IV: Non-Classical Telomere Structures. 27. Telomeres in Drosophila and Other Insects; H. Biessmann, et al. 28. Mitochondrial Telomeres: Alternative Solutions to the End-Replication Problem; J. Nosek, L. Tomaska. Index.