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Genetics of Common Diseases Ian Day (University of Southampton, England, UK)

Genetics of Common Diseases By Ian Day (University of Southampton, England, UK)

Genetics of Common Diseases by Ian Day (University of Southampton, England, UK)

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Summary

Many common diseases are partly attributable to the genes which an individual inherits

Genetics of Common Diseases Summary

Genetics of Common Diseases: Future Therapeutic and Diagnostic Possibilities by Ian Day (University of Southampton, England, UK)

Many common diseases are partly attributable to the genes which an individual inherits. Early steps have now been made in developing ways to determine which genetic variations are important, with some recent successes. In parallel, ways to improve healt

Genetics of Common Diseases Reviews

I recommend this book as a good introduction to this exciting area. BMJ; ; In summary, this book is an interesting and very informative attempt to bring together aspects of our rapidly increasing knowledge of the genetics of common diseases, with poss

About Ian Day (University of Southampton, England, UK)

Department of Medicine, University College London Medical School, The Rayne Institute, London, UK (address from October 1997: Wessex Human Genetics Institute, Southampton University Hospital, Southampton, UK). Department of Medicine, University College London Medical School, The Rayne Institute, London, UK.

Table of Contents

Contributors -- Abbreviations -- Preface -- 1 Perspectives in human linkage studies. /S. Povey -- Pairwise linkage analysis of Mendelian traits -- Finding the cause of a disease which shows clear Mendelian inheritance -- After a LOO score of +3, what next? -- Narrowing the search by searching for critical recombinants -- Linkage disequilibrium -- Linkage analysis in more complex situations -- Linkage in complex traits -- Why are we doing this? -- References -- 2 Twin research: nature versus nurture in common diseases. /K.O. Kyvik -- Introduction -- History -- Biology of twinning -- Demography -- Twin studies -- Assumptions -- T he concept of concordance rates -- Heritability -- Twin studies and common diseases -- Other types of twin studies -- Conclusion -- References -- 3 The molecular basis of genetic variation: mutation detection methodologies and limitations. /E. Spanakis and I.N.M. Day -- Introduction -- Current theories of mutation -- Parallel development of theory with methodology -- Methods of mutation detection -- Limitations of current methods for mutation detection -- Our approaches -- Conclusions -- References -- 4 Finding susceptibility genes for schizophrenia. /M.J. Owen and M.C. O'Donovan -- Introduction -- Molecular genetic approaches to schizophrenia -- Candidate gene association studies -- Conclusions -- References -- 5 Approaches to determining the genetic basis of noninsulin-dependent diabetes mellitus. /M. McCarthy -- Non-insulin-dependent diabetes mellitus (NIDDM) -- Overview of approaches to dissect NIDDM -- Choosing a candidate gene -- Exploring candidate genes -- Assessing genotype-phenotype correlations -- Understanding the biology of complex traits -- References -- 6 Population-scale genotype assays: APOE gene in Alzheimer's dementia and coronary risk. /I.N.M. Day, D. Palamand and E. Spanakis -- Introduction: availability of population-scale gene testing -- Background -- Some future possibilities -- References -- 7 Genetic tests for corona

Additional information

GOR013379686
9781859960417
1859960413
Genetics of Common Diseases: Future Therapeutic and Diagnostic Possibilities by Ian Day (University of Southampton, England, UK)
Ian Day (University of Southampton, England, UK)
Used - Good
Hardback
Taylor & Francis Ltd
19970615
344
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
This is a used book - there is no escaping the fact it has been read by someone else and it will show signs of wear and previous use. Overall we expect it to be in good condition, but if you are not entirely satisfied please get in touch with us

Customer Reviews - Genetics of Common Diseases