Cart
Free US shipping over $10
Proud to be B-Corp

Neuroprotection in Alzheimer's Disease Summary

Neuroprotection in Alzheimer's Disease by Illana Gozes (Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Israel)

Neuroprotection in Alzheimers Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimers disease will pave the path to better disease management and novel therapeutics.

About Illana Gozes (Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Israel)

Dr. Illana Gozes is a Professor Emerita at the Sackler Faculty of Medicine and is a faculty of the Sagol School of Neuroscience and Adams Super Center for Brain Studies at Tel Aviv University in Tel Aviv, Israel. She is the incumbent of the Lily and Avraham Gildor Chair for the Investigation of Growth Factors and Heads the Elton Laboratory for Molecular Neuroendocrinology. Prof. Gozes won many awards of excellence (including Bergmann Award, Fogarty-Scholar-in-Residence, Tel Aviv Universitys Vice President Award-best applied scientist, Olson Prize, Julodan Prize, Teva Prize, Neufeld Award, Hanse-Wissenschaftskolleg (HWK) fellowship, Humboldt Award, Landau Prize for Life Achievements and Champion of Hope Science International -2016, Global Genes, USA. She is an Ex-President of the Israel Society for Neuroscience, served on the Governing Committee and the Board of Governors of Tel Aviv University, and is currently serving on the Council of the European Society for Neurochemistry, the Israeli Ministry of Education, Council of Higher Education and is the Israeli coordinator of the International Brain Bee Competition for high school students and the Editor-in-Chief of the Journal of Molecular Neuroscience and serves on many journal editorial boards. Professor is the inventor of numerous patents including CP201(NAP, davunetide), a clinical drug candidate targeted at the rare disease indication, the ADNP syndrome (founded Allon Therapeutics and currently Chief Scientific Officer at Coronis Neurosciences). Professor Gozes discovered ADNP, an essential protein for brain formation implicated in autism, schizophrenia, Alzheimers disease and cancer. CP201 is a snippet of ADNP, enhancing ADNPs protective activity. Professor Gozes published >320 papers and has an h-index of 73 (Google Scholar).

Table of Contents

1. Introduction 2. Neural regeneration as a disease modifying therapeutic strategy for Alzheimer's disease 3. Animal models 4. Mechanisms of Neuronal Microtubule Loss in Alzheimers Disease 5. Tau-centric therapies for treating Alzheimers Disease 6. The potential of small molecules in preventing tau oligomers formation and toxicity 7. A novel neuroprotection target with distinct regulation in stroke and Alzheimers disease 8. Sirtuin modulation as novel neuroprotective strategy for Alzheimer's Disease 9. Rescue of neurons by resolving inflammation 10. Targeting transition metals for neuroprotection in Alzheimers disease 11. Multifunctional effect of human serum albumin towards neuroprotection in Alzheimer disease 12. RGS2 and SIRT1 link renin angiotensin aldosterone system to Alzheimers disease 13. Neuroprotective drug development: the story of ADNP, NAP (davunetide) and SKIP

Additional information

NPB9780128036907
9780128036907
0128036907
Neuroprotection in Alzheimer's Disease by Illana Gozes (Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Israel)
New
Hardback
Elsevier Science Publishing Co Inc
2017-01-17
342
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
This is a new book - be the first to read this copy. With untouched pages and a perfect binding, your brand new copy is ready to be opened for the first time

Customer Reviews - Neuroprotection in Alzheimer's Disease