Part 1: Introduction. 1. The chromogranins: Historical perspectives; K.B. Helle. 2. Chromogranins - Current concepts: Structural and functional aspects; D. Aunis, M.-H. Metz-Boutigue. Part 2: Intracellular Functions. 3. Signal-mediated sorting of chromogranins to secretory granules; H.-H. Gerdes, M.H. Gombik. 4. The condensed matrix of mature chromaffin granules: The soluble form of dopamine beta-hydroxyase is catalytically inactive; O. Terland, T. Flatmark. 5. Functional role of chromogranins: The intragranular matrix in the last phase of exocytosis; R. Borges, et al. 6. Inositol 1,4,5-trisphosphate receptor and chromogranins A and B in secretory granules. Co-localization and functional coupling; S.H. Yoo, et al. Part 3: Transcription, Expression and Secretion. 7. Regulation of chromogranin A transcription and catecholamine secretion by the neuropeptide PACAP. Stimulation and desensitization; L. Taupenot, et al. 8. Neuroendocrine cell-specific expression and regulation of human secretogranin II gene; Y. Anouar, et al. 9. Characterization of chromogranins in the frog Rana ridibunda. Structure, expression and functional implications; V. Turquier, et al. 10. Expression of equine chromogranin A. cDNA sequence and distribution of mRNA in endocrine and exocrine tissues; F. Sato, et al. 11. Salivary secretion of chromogranin A. Control by autonomic nervous system; T. Kanno, et al. Part 4: Tissue-Specific Processing, Transport and Distribution. 12. Proteolytic processing of chromogranins; A. Laslop, et al. 13. Endothelial handling of chromogranin A; M. Mandala, et al. 14. Tissue plasminogen activator and chromogranin cell function; R.J. Parmer, et al. 15. Chromogranin A immunoreactivity in neuroendocrine cells in the human gastrointestinal tract and pancreas; G.M. Portela-Gomes. 16. Chromogranin A and its derived peptides in the rat and porcine gastro-entero-pancreatic system. Expression, localization and characterization; W.J. Curry, et al. Part 5: Functional Aspects of Biologically Active Sequences. 17. Regulation of parathyroid secretion. Chromogranins, chemokines and calcium; R. Hogue, et al. 18. Vasostatins. Vascular targets; K.B. Helle. 19. Vasostatins. Dilators of bovine resistance arteries; J.F. Brekke, et al. 20. Pancreastatin: Biological effects and mechanisms of action; V. Sanchez-Margalet, et al. 21. The novel catecholamine release-inhibitory peptide catestatin (chromogranin A 344-364). Properties and function; S.K. Mahata, et al. 22. Secretoneurin &endash; A novel link between the nervous and the immune system. Conservation of the sequence and functional aspects; C.M. Kahler, R. Fischer-Colbrie. 23. Chromogranin A induces a neurotoxic phenotype in brain microglial cells; J. Ciesielski-Treska, C. Aunis. 24. Antibacterial and antifungal peptides derived from chromogranins and proenkephalin-A. From structural to biological aspects; M.-H. Metz-Boutigue, et al. Part 6: Clinical Aspects of the Circulating Prohormones. 25. Measurements of chromogranins and chromogranin-related peptides by immunological met
