This work talks about organic synthesis with enzymes - the only way. This comprehensive manual gives reliable answers to all questions on enzyme catalysis - from searching for suitable catalytic converter systems via choosing the optimal reaction conditions to implementing modern synthesis strategies. The long-awaited new edition has been greatly expanded to include new topics and to reflect the latest research, yet retains the clear and practice-oriented presentation found in the first edition. More than a mere data collection, the three volumes provide synthetic chemists with easy access to all the first-hand information necessary for successfully using enzymes - the latest synthesis methods; example applications arranged according to reaction type; a table of all the important, commercially available enzymes; comprehensive registers for targeted searching according to enzyme, compound, or reaction; modern methods of protein chemistry: use of catalytic anti-bodies and protein engineering; and current references to the literature. In short, it is an indispensable reference that should be on the shelf of every modern synthesis laboratory.