In transdiagnostic emotion-focused therapy (EFT-T), therapists target deep core emotional vulnerability-- sadness/loneliness, shame, and fear/terror-that underlie the diagnostic cluster depression, anxiety, and related disorders, such as posttraumatic stress disorder and obsessive-compulsive disorder. Part I presents the theoretical underpinnings of EFT-T. Part 2, a clinical guide for therapists, describes specific techniques to use with emotionally overwhelmed as well as emotionally restricted clients, such as two-chair dialogues and self-interruption, all of which are illustrated through richly detailed session transcripts.