Preface
Contributors
Part I. The Normal Upper Airway
1. Upper Airway Structure During Development
Seung Hoon Lee
2. Functional Aspects and Upper Airway Control During Wakefulness and Sleep
Neriel Katz, Tamar Etzioni and Giora Pillar
3. Lymphadenoid Tissues in the Upper Airway
Jinkwan Kim and David Gozal
4. The Nasal Airway
Fuad M. Baroody
Part II. Sleep During Development
5. Neural Mechanisms of Sleep and Circadian Rhythms
Edgar Garcia-Rill
6. EEG and Sleep During Development
Raffaele Ferri, Luana Novelli, and Oliviero Bruni
7. Autonomic Cardiovascular Regulation during Sleep
Anna Kourbasis, Lisa M. Walter, Stephanie R. Yiallourou, and Rosemary S. C. Horne
8. Arousal: Ontology, Functional Anatomy, Methodology, and Consequences
Eliot S. Katz
9. Metabolic and Hormonal Regulation during Sleep
Riva Tauman
10. Chemoreceptors, Breathing, and Sleep
John L. Carroll, Supriya K. Jambhekar, and David F. Donnelly
11. Pathophysiology of Pediatric Obstructive Sleep Apnea: Putting it All Together
Eliot S. Katz
Part III. Diagnostic Assessment of Sleep and Breathing in Children
12. Clinical Evaluation of the Pediatric Patient
Hari P. R. Bandla
13. Actigraphy
Hawley E. Montgomery-Downs and Lisa J. Meltzer
14. Abbreviated/Portable Recordings
Luigi Ferini-Strambi
15. Overnight Sleep Study and MSLT
Jyoti Krishna
16. Upper Airway Imaging in Children with Obstructive Sleep Apnea Syndrome
Raanan Arens and Sanghun Sin
17. The Omics Future: Genomics, Transcriptomics, and Proteomics
Sina A. Gharib
18. Pediatric Sleep Disordered Breathing: Criteria and Spectrum of Disease
Karen Spruyt
Part IV. SDB in Children
19. Apnea of Prematurity
Christian F. Poets
20. Epidemiologic Aspects of Pediatric OSA around the World
Athanasios Kaditis
21. Obesity and Sleep
Edward O. Bixler, Alexandros N. Vgontzas, Marina Tsaoussoglou, and Susan L. Calhoun
22. Obstructive Sleep Apnea in Children with Down Syndrome
Dennis Rosen
23. Children with Neuromuscular Disorders
Aviv D. Goldbart
24. Sleep Problems in Children with Sickle Cell Disease
Umakanth Khatwa, Alia Bazzy-Asaad, and Sanjeev V. Kothare
25. Children with Craniofacial Syndromes
Wendy Estrellado-Cruz and Robert C. Beckerman
26. Epilepsy, Headache, and Sleep Disordered Breathing
Martina Vendrame and Sanjeev V. Kothare
27. Sleep and Breathing in Cystic Fibrosis
Amanda J. Piper
28. Asthma and Obstructive Sleep Apnea
Leila Kheirandish-Gozal
29. Central Hypoventilation Syndromes
Iris A. Perez, Thomas G. Keens, and Sally L. Davidson Ward
30. Healthcare Utilization and Pediatric Obstructive Sleep Apnea
Ariel Tarasiuk and Haim Reuveni
31. Gastroesophageal Reflux and Sleep Disordered Breathing
Hari P. R. Bandla and Aparna R. Rao
Part V. Consequences of SDB in Children
32. Behavioral Morbidity in Pediatric Sleep Disordered Breathing
Elise K. Hodges, Barbara True Felt, Bruno J. Giordani, and Ronald D. Chervin
33. Neurocognitive Function and Learning in Children with Sleep Disordered Breathing
Karen Spruyt
34. Brain Regulatory Mechanisms Underlying Breathing: Insights for Sleep Pathology
Ronald M. Harper, Rajesh Kumar, Paul M. Macey, Jennifer A. Ogren, and Mary A. Woo
35. Cardiovascular Implications
Rakesh Bhattacharjee and Leila Kheirandish-Gozal
36. Metabolic Consequences of Sleep Disorders
David Gozal
37. Enuresis and Obstructive Sleep Apnea in Children
Oscar Sans Capdevila and Maria Eugenia Russi Delfraro
Part VI. Treatment of SDB
38. Adenotonsillectomy
Rakesh Bhattacharjee
39. Corticosteroids and Leukotriene Modifiers in Pediatric SDB
Aviv D. Goldbart and Leila Kheirandish-Gozal
40. CPAP Treatment in Children
Dafna Ofer and Carole L. Marcus
41. Mandibular Advancement Devices
Maria Pia Villa and Silvia Miano
42. Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome (CCHS)
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
42. Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome (CCHS)
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
Part VI. Treatment of SDB
38. Adenotonsillectomy
Rakesh Bhattacharjee
39. Corticosteroids and Leukotriene Modifiers in Pediatric SDB
Aviv D. Goldbart and Leila Kheirandish-Gozal
40. CPAP Treatment in Children
Dafna Ofer and Carole L. Marcus
41. Mandibular Advancement Devices
Maria Pia Villa and Silvia Miano
42. Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome (CCHS)
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
Part VI. Treatment of SDB
38. Adenotonsillectomy
Rakesh Bhattacharjee
39. Corticosteroids and Leukotriene Modifiers in Pediatric SDB
Aviv D. Goldbart and Leila Kheirandish-Gozal
40. CPAP Treatment in Children
Dafna Ofer and Carole L. Marcus
41. Mandibular Advancement Devices
Maria Pia Villa and Silvia Miano
42. Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome (CCHS)
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
Hawley E. Montgomery-Downs and Lisa J. Meltzer
14. Abbreviated/Portable Recordings
Luigi Ferini-Strambi
15. Overnight Sleep Study and MSLT
Jyoti Krishna
16. Upper Airway Imaging in Children with Obstructive Sleep Apnea Syndrome
Raanan Arens and Sanghun Sin
17. The Omics Future: Genomics, Transcriptomics, and Proteomics
Sina A. Gharib
18. Pediatric Sleep Disordered Breathing: Criteria and Spectrum of Disease
Karen Spruyt
Part IV. SDB in Children
19. Apnea of Prematurity
Christian F. Poets
20. Epidemiologic Aspects of Pediatric OSA around the World
Athanasios Kaditis
21. Obesity and Sleep
Edward O. Bixler, Alexandros N. Vgontzas, Marina Tsaoussoglou, and Susan L. Calhoun
22. Obstructive Sleep Apnea in Children with Down Syndrome
Dennis Rosen
23. Children with Neuromuscular Disorders
Aviv D. Goldbart
24. Sleep Problems in Children with Sickle Cell Disease
Umakanth Khatwa, Alia Bazzy-Asaad, and Sanjeev V. Kothare
25. Children with Craniofacial Syndromes
Wendy Estrellado-Cruz and Robert C. Beckerman
26. Epilepsy, Headache, and Sleep Disordered Breathing
Martina Vendrame and Sanjeev V. Kothare
27. Sleep and Breathing in Cystic Fibrosis
Amanda J. Piper
28. Asthma and Obstructive Sleep Apnea
Leila Kheirandish-Gozal
29. Central Hypoventilation Syndromes
Iris A. Perez, Thomas G. Keens, and Sally L. Davidson Ward
30. Healthcare Utilization and Pediatric Obstructive Sleep Apnea
Ariel Tarasiuk and Haim Reuveni
31. Gastroesophageal Reflux and Sleep Disordered Breathing
Hari P. R. Bandla and Aparna R. Rao
Part V. Consequences of SDB in Children
32. Behavioral Morbidity in Pediatric Sleep Disordered Breathing
Elise K. Hodges, Barbara True Felt, Bruno J. Giordani, and Ronald D. Chervin
33. Neurocognitive Function and Learning in Children with Sleep Disordered Breathing
Karen Spruyt
34. Brain Regulatory Mechanisms Underlying Breathing: Insights for Sleep Pathology
Ronald M. Harper, Rajesh Kumar, Paul M. Macey, Jennifer A. Ogren, and Mary A. Woo
35. Cardiovascular Implications
Rakesh Bhattacharjee and Leila Kheirandish-Gozal
36. Metabolic Consequences of Sleep Disorders
David Gozal
37. Enuresis and Obstructive Sleep Apnea in Children
Oscar Sans Capdevila and Maria Eugenia Russi Delfraro
Part VI. Treatment of SDB
38. Adenotonsillectomy
Rakesh Bhattacharjee
39. Corticosteroids and Leukotriene Modifiers in Pediatric SDB
Aviv D. Goldbart and Leila Kheirandish-Gozal
40. CPAP Treatment in Children
Dafna Ofer and Carole L. Marcus
41. Mandibular Advancement Devices
Maria Pia Villa and Silvia Miano 42. Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome (CCHS)
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
42. Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome (CCHS)
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
Part VI. Treatment of SDB
38. Adenotonsillectomy
Rakesh Bhattacharjee
39. Corticosteroids and Leukotriene Modifiers in Pediatric SDB
Aviv D. Goldbart and Leila Kheirandish-Gozal
40. CPAP Treatment in Children
Dafna Ofer and Carole L. Marcus
41. Mandibular Advancement Devices
Maria Pia Villa and Silvia Miano
42. Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome (CCHS)
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
28. Asthma and Obstructive Sleep Apnea
Leila Kheirandish-Gozal
29. Central Hypoventilation Syndromes
Iris A. Perez, Thomas G. Keens, and Sally L. Davidson Ward
30. Healthcare Utilization and Pediatric Obstructive Sleep Apnea
Ariel Tarasiuk and Haim Reuveni
31. Gastroesophageal Reflux and Sleep Disordered Breathing
Hari P. R. Bandla and Aparna R. Rao
Part V. Consequences of SDB in Children
32. Behavioral Morbidity in Pediatric Sleep Disordered Breathing
Elise K. Hodges, Barbara True Felt, Bruno J. Giordani, and Ronald D. Chervin
33. Neurocognitive Function and Learning in Children with Sleep Disordered Breathing
Karen Spruyt
34. Brain Regulatory Mechanisms Underlying Breathing: Insights for Sleep Pathology
Ronald M. Harper, Rajesh Kumar, Paul M. Macey, Jennifer A. Ogren, and Mary A. Woo
35. Cardiovascular Implications
Rakesh Bhattacharjee and Leila Kheirandish-Gozal
36. Metabolic Consequences of Sleep Disorders
David Gozal
37. Enuresis and Obstructive Sleep Apnea in Children
Oscar Sans Capdevila and Maria Eugenia Russi Delfraro
Part VI. Treatment of SDB
38. Adenotonsillectomy
Rakesh Bhattacharjee
39. Corticosteroids and Leukotriene Modifiers in Pediatric SDB
Aviv D. Goldbart and Leila Kheirandish-Gozal
40. CPAP Treatment in Children
Dafna Ofer and Carole L. Marcus
41. Mandibular Advancement Devices
Maria Pia Villa and Silvia Miano
42. Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome (CCHS)
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
42. Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome (CCHS)
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
Part VI. Treatment of SDB
38. Adenotonsillectomy
Rakesh Bhattacharjee
39. Corticosteroids and Leukotriene Modifiers in Pediatric SDB
Aviv D. Goldbart and Leila Kheirandish-Gozal
40. CPAP Treatment in Children
Dafna Ofer and Carole L. Marcus
41. Mandibular Advancement Devices
Maria Pia Villa and Silvia Miano
42. Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome (CCHS)
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
42. Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome (CCHS)
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer
Anthony C. Chin, Donald B. Shaul, Pallavi P. Patwari, Thomas G. Keens, Anna S. Kenny, and Debra E. Weese-Mayer