Foreword. Preface. Introduction. Chapter 1 - Assessment. A step by step approach to history taking. The functional enquiry. Physical examination. The cardiovascular examination. The respiratory examination. The abdominal examination. The neurological examination. Psychiatric history and examination. Chapter 2 - Emergencies. The assessment, investigation, diagnosis and management of: Acute anaphylaxis. Cardio-respiratory arrest. Chapter 3 - Acute poisoning and drug overdose. The assessment, investigation, diagnosis and management of: Paracetamol overdose. Aspirin overdose. Tricyclic overdose. Alcohol overdose. Alcohol withdrawal. Drug withdrawal. Chapter 4 - Infection. The assessment, investigation, diagnosis and management of: Sepsis and septic shock. Meningitis. Infective endocarditis. Gastroenteritis. Urinary Tract Infection. Fever in the returning traveller. Hot swollen joints. Chapter 5 - Respiratory conditions. The assessment, investigation, diagnosis and management of: Asthma. Chronic Obstructive Pulmonary Disease. Pulmonary Embolism. Pneumothorax. Community Acquired Pneumonia. Hospital Acquired Pneumonia. Type I Respiratory Failure. Type II Respiratory Failure. Chapter 6 - Cardiovascular conditions. The assessment, investigation, diagnosis and management of: Acute Coronary Syndromes. Acute Myocardial Infarction. Arrhythmias. Atrial Fibrillation. Cardiac Failure. Deep Vein Thrombosis. Aortic dissection. Cardiac tamponade. Chapter 7 - Gastrointestinal conditions. The assessment, investigation, diagnosis and management of: Upper gastrointestinal haemorrhage. Acute liver failure and encephalopathy. Ulcerative colitis and Crohns disease. Chapter 8 - Metabolic conditions. The assessment, investigation, diagnosis and management of: Diabetic Ketoacidosis. Non-Ketotic Hyperosmolar Coma. Hypoglycaemia. Hyperglycaemia in the critically ill patient. Hypercalcaemia. Hyponatraemia. Hypernatraemia. Hypokalaemia. Hyperkalaemia. Addisonian crisis. Thyroid crisis. Myxedema crisis. Chapter 9 - Neurological conditions. The assessment, investigation, diagnosis and management of: Status Epilepticus. Stroke. Isolated seizure and unexplained loss of consciousness. Headache. Subarachnoid haemorrhage. Chapter 10 - Renovascular conditions. The assessment, investigation, diagnosis and management of: Acute Renal Failure. Accelerated (malignant) hypertension. Chapter 11 - Elderly Care. The assessment, investigation, diagnosis and management of: Hypothermia. Confusion. Chapter 12 - Haematological conditions. The assessment, investigation, diagnosis and management of: Severe anaemia. Sickle cell crisis. Neutropenic sepsis. Blood transfusion guidance. Chapter 13 - Advanced Practice. Legal, ethical and professional issues. Informed consent. Assessment of capacity. Role Development. Prescribing. Appendices. Examples of:. Clinical Management Plans. Patient Group Directions. Glossary. Subject Index.