ITALY, 1492. Five-year-old Mura is a strange and bewitching child. Daughter of a Nordic mother and Spanish father, she has been tutored in both Arabic learning and the ancient mythology of the north. But when her widower father is taken by the Inquisition, Mura is sold to a Genoese slaver. In the port of Savona, Mura's androgynous looks and unusual abilities fetch a high price. She is bought as a house slave for the powerful Medici, arriving in Florence as the city prepares for war against the French. When the family are forced to flee, Mura finds herself gifted to the notorious Lioness of Romagna, Countess Caterina Sforza. Beautiful, ruthless and intelligent, the Countess is fascinated by Mura's arcane knowledge. As the Lioness educates her further in the arts of alchemy, potions and poisons, Mura becomes a potent weapon in the Machiavellian intrigues of the Renaissance court...