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In Silico Systems Biology Maria Victoria Schneider

In Silico Systems Biology By Maria Victoria Schneider

In Silico Systems Biology by Maria Victoria Schneider


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Summary

This Methods in Molecular Biology(TM) book offers detailed coverage of current techniques in network biology and mathematical models of biological systems. Includes step-by-step workflows, as well as key tips on troubleshooting and avoiding known pitfalls.

In Silico Systems Biology Summary

In Silico Systems Biology by Maria Victoria Schneider

Systems biology can now be considered an established and fundamental field in life sciences. It has moved from the identification of molecular 'parts lists' for living organisms towards synthesising information from different 'omics'-based approaches to generate and test new hypotheses about how biological systems work. In In Silico Systems Biology: Methods and Protocols, expert researchers in the field detail a practical set of chapters based often on actual materials used and develop for face-to-face training with examples and case studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step workflows, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, In Silico Systems Biology: Methods and Protocols seeks to aid scientists in the further study of network biology and mathematical models of biological systems.

Table of Contents

1. Defining Systems Biology: A Brief Overview of the Term and Field

Maria Victoria Schneider

2. Approaches to Modelling Gene Regulatory Networks - A Gentle Introduction

Thomas Schlitt

3. Integration of Genomic Information with Biological Networks using Cytoscape

Anna Bauer-Menren

4. Visualization and Analysis of Biological Networks

Pablo Porras Millan

5. Modeling Signaling Networks with Different Formalisms: A Preview

Aidan MacNamara, David Henriques, and Julio Saez-Rodriguez

6. From a Biological Hypothesis to the Construction of a Mathematical Model

David Cohen, Inna Kuperstein, Emmanuel Barillot, Andrei Zinovyev and Laurence Calzone

7. Practical use of BiNoM, a Biological Network Manager Software

Eric Bonnet, Laurence Calzone, Daniel Rovera, Gautier Stoll, Emmanuel Barillot, and Andrei Zinovyev

8. Using Chemical Kinetics to Model Biochemical Pathways

Nicolas Le Novere and Lukas Endler

9. Simulation of Stochastic Kinetic

Models

Andrew Golightly and Colin S. Gillespie

10. BioModels Database: A Repository of Mathematical Models of Biological Processes

Vijayalakshmi Chelliah, Camille Laibe, and Nicolas Le Novere

11. Supporting SBML as a Model Exchange Format in Software

Applications

Sarah M. Keating and Nicolas Le Novere

12. Controlled Annotations for Systems Biology

Nick Juty, Camille Laibe, and Nicolas Le Novere

13. Bayesian Approaches for Mechanistic

Ion Channel Modelling

Ben Calderhead, Michael Epstein, Lucia Sivilotti, Mark Girolami

14. Building Models using Reactome Pathways as Templates

David Croft

15. Uniform Curation Protocol of Metazoan Signaling Pathways to Predict Novel Signaling Components

Mate Palfy, Illes J. Farkas, Tibor Vellai, and Tamas Korcsmaros

16. Bioinformatics Workflows and Web-services in Systems Biology Made Easy for Experimentalists

Rafael C. Jimenez and Manuel Corpas

Additional information

NLS9781493962952
9781493962952
1493962957
In Silico Systems Biology by Maria Victoria Schneider
New
Paperback
Humana Press Inc.
2016-08-23
313
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
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