Jane Doe had been a promising anthropologist, an expert on shamanism. Now she is nothing, a shadow. After faking her own suicide, she is living under an assumed identity in Miami, with a traumatised little girl to protect. Everyone thinks Jane is dead - or so she hopes.

Then the killings start: a series of ritualistic murders that terrifies the entire city. The investigating detective, Jimmy Paz, locates the witnesses to these events but they can recall almost nothing, as though their memories have been erased. As if a spell has been cast on them...

A bizarre string of clues eventually points towards the fugitive, Jane Doe, and force her to realize the darkness she has fled is deliberately seeking her out, hunting her down. And when their two paths inexorably intersect, the two of them will be thrust into a cataclysmic battle between good and evil unimaginable to the Western mind.