Introduction; 1. Parkinson's disease: an overview of non-motor symptomatology Valentina Leta, Daniel van Wamelen and Ray Chaudhuri; 2. Evaluation of the patient with Parkinson's disease in the early stages: non-motor phase Anna Sauerbier, Daniele Urso, Chloe Farrell, K. Ray Chaudhuri and Carmen Rodriguez-Blazquez; 3. Non-motor symptoms in late-stage Parkinson's disease Umar Shuaib, Adam Margolius and Hubert Fernandez; 4. Neuropathology of non-motor Parkinson's disease symptoms Lea Grinberg and Helmut Heinsen; 5. Neuroimaging studies in non-motor Parkinson's disease symptoms David Brooks; 6. Mild cognitive impairment Amos D. Korczyn; 7. Cognitive dysfunction in Parkinson's disease Damon Salzman and Shakeel Tabish; 8. Neuropsychiatric (behavioral) symptoms in Parkinson's disease Kasia Rothenberg; 9. Mood disorders in patients with Parkinson's disease Po-Heng Tsai and Ganesh Gopalakrishna; 10. Olfactory dysfunction in Parkinson's disease and related disorders Richard Doty and Christopher Hawkes; 11. Oculomotor and visual-vestibular disturbances in Parkinson's disease Adolfo Bronstein, Aasef Shaikh, Tim Anderson, Michael MacAskill and Diego Kaski; 12. Autonomic dysfunction and failure in Parkinson's disease Thomas Foki, Birgit Riemer, Bianca Brim and Walter Struhal; 13. Gastrointestinal disturbances in Parkinson's disease, including the management of Sialorrhea Wolfgang H. Jost and Lisa Klingelhoefer; 14. Sexual dysfunction in Parkinson's disease Gila Bronner and Tanya Gurevich; 15. Sleep disturbances in Parkinson's disease, including rapid eye movement behavior disorders Cristian Falup-Pecurariu, Stefania Diaconu and Maria-Lucia Muntean; 16. Musculoskeletal disorders and pain in Parkinson's disease Ovidiu Bajenaru; 17. Cutaneous manifestations of Parkinson's disease Rivka Inzelberg and Esther Azizi; 18. Genetics of non-motor symptoms of Parkinson's disease Ziv Gan-Or, Konstantin Senkevich and Roy Alcalay; 19. Drug-induced non-motor symptoms of Parkinson's disease Camila Aquino; 20. Impulse control disorders and the dopamine dysregulation syndrome Atbin Djamshidian, Guillaume Pagnier, Michael J Frank and Joseph H. Friedman; 21. Serotonin syndrome and drug interactions, hypertensive complications, and adverse effects of Monoamine oxidase inhibitors in patients with Parkinson's disease Kailash Bhatia and Eoin Mulroy; 22. Parkinson's disease and pregnancy Shira McMahan, Ramon Lugo-Sanchez and Nestor Galvez-Jimenez.