The fully updated Fourth Edition of this comprehensive clinical reference summarizes the latest data on hundreds of drug and device-based therapies and offers practical, evidence-based guidelines and treatment strategies for virtually every psychiatric disorder. Coverage includes the recently FDA-approved use of vagus nerve stimulation for treatment-resistant depression and current clinical guidelines on electroconvulsive therapy and transcranial magnetic stimulation, including indications, dosage, variations in treatment, and administration. Other topics addressed include the risks and benefits of psychopharmacotherapy for the pregnant, child, adolescent, geriatric, and dementia patient, and up-to-the-minute strategies for treating schizophrenia, bipolar disorder, anxiety, sleep disorders, obsessive-compulsive and panic disorders, dementia, and more.