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Basic Concepts of Molecular Pathology Philip T. Cagle

Basic Concepts of Molecular Pathology By Philip T. Cagle

Basic Concepts of Molecular Pathology by Philip T. Cagle


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Summary

Aimed at the pathologist, clinician and radiologist, this concise review covers the essential terminology, concepts and tools of molecular biology as applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine.

Basic Concepts of Molecular Pathology Summary

Basic Concepts of Molecular Pathology by Philip T. Cagle

Over the past two decades there has been an explosion in knowledge about the molecular pathology of human diseases which accelerated with the sequencing of the human genome in 2003. Molecular diagnostics and molecular targeted therapy have contributed to the current concept of personalized patient care that is now routine in many medical centers. As a result, general and subspecialty pathologists, clinical practitioners of all types and radiologists must now have an understanding of the basic concepts of molecular pathology and their role in new diagnostic and therapeutic applications to patient care.

The Molecular Pathology Library series was created to bridge the gap between traditional basic science textbooks in molecular biology and traditional medical textbooks for organ-specific diseases. Basic Concepts of Molecular Pathology is designed as a stand-alone book to provide the pathologist, clinician or radiologist with a concise review of the essential terminology, concepts and tools of molecular biology that are applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine.

Those medical practitioners, residents, fellows and students who need to refer to the terminology and concepts of molecular pathology in their patient care will find the Basic Concepts of Molecular Pathology to be a succinct, portable, user-friendly aid in their practice and studies. The service-based physician will find this handy reference to be valuable at the laboratory benchside, at the patient bedside, at multidisciplinary patient care conferences or as a review for examinations.

Basic Concepts of Molecular Pathology Reviews

From the reviews:

This book concisely presents basic concepts of molecular biology and applied molecular pathology. ... written for anyone interested in basic molecular pathology concepts. It would be of interest to physicians ... interested in adaptation of molecular biology concepts to pathologic diagnosis. It would also be of interest to those wanting a single reference to update their knowledge of molecular biology and applied molecular pathology. ... a great book for anyone wanting a concise and broad overview or review of molecular biology and applied molecular pathology. (Valerie L Ng, Doody's Review Service, October, 2009)

Table of Contents

Genes, Gene Products, and Transcription Factors.- Receptors, Signaling Pathways, Cell Cycle, and DNA Damage Repair.- Cell Adhesion Molecules.- Apoptosis and Cell Death.- The Role of Mutation and Epimutation in the Development of Human Disease.- Bioinformatics and Omics.- General Approach to Molecular Pathology.- Applications in Anatomic Pathology.- Polymerase Chain Reaction and Reverse Transcription-Polymerase Chain Reaction.- Array Comparative Genomic Hybridization in Pathology.- Loss of Heterozygosity.- In Situ Hybridization: Principles and Applications.- Proteomics.- Immunohistochemistry of Biomarkers.- Basic Principles of Flow Cytometry.- Stem Cells.- Animal Models of Lung Disease.- Tissue Culture Models.

Additional information

NLS9780387896250
9780387896250
0387896252
Basic Concepts of Molecular Pathology by Philip T. Cagle
New
Paperback
Springer-Verlag New York Inc.
2009-06-25
190
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
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Customer Reviews - Basic Concepts of Molecular Pathology