This comprehensive reference guide describes more than 130 alphabetically arranged drugs of abuse, including both pharmaceutical and natural products. The book begins with a discussion of federal drug scheduling and drug categories. Individual entries for particular substances of abuse follow. Drug descriptions include: correct pronunciation, nicknames or street names, legal status, historical and present uses and misuses, abuse factors, interactions with other drugs, and findings of cancer risks and birth defects.

Scientific information is presented in a clear, simple manner designed for students and general readers alike. In addition to the A-Z descriptions, Miller provides an explanation of general drug types, such as stimulants and hallucinogens, as well as the aspects of drug abuse, including tolerance and withdrawal. A list of print and electronic sources is also included for readers seeking further information.