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Physical Biology of the Cell Rob Phillips (California Institute of Technology, USA)

Physical Biology of the Cell By Rob Phillips (California Institute of Technology, USA)

Physical Biology of the Cell by Rob Phillips (California Institute of Technology, USA)


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Summary

Explores how the basic tools and insights of physics and chemistry are able to illuminate the study of molecular and cellular biology. Drawing upon examples and seminal experiments from cell biology, this book demonstrates how fundamental, quantitative models can help refine understanding of biological data and also be used to make predictions.

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Physical Biology of the Cell Summary

Physical Biology of the Cell by Rob Phillips (California Institute of Technology, USA)

Physical Biology of the Cell is a biophysics textbook that explores how the basic tools and insights of physics and mathematics can illuminate the study of molecular and cell biology. Drawing on key examples and seminal experiments from cell biology, the book demonstrates how quantitative models can help refine our understanding of existing biological data and also be used to make useful predictions. The book blends traditional models in cell biology with the quantitative approach typical in physics, in order to introduce the reader to both the possibilities and boundaries of the emerging field of physical biology. While teaching physical model building in cell biology through a practical, case-study approach, the text explores how quantitative modeling can be used to build a more profound, intuitive understanding of cell biology.

Physical Biology of the Cell Reviews

...[The] authors of Physical Biology of the Cell have produced one of the first multi-purpose textbooks that is readily accessible to both physicists and biologists.... When read from cover to cover, the book is both very instructive and highly entertaining with the authors using humour to deliver strong take-home messages in each chapter....Physical Biology of the Cell provides instructors with excellent material to create a graduate level course in biology or physics. The book is also very timely as it presents the most recent views in cell biology. As physicists, we strongly agreed with the message of the authors, but will this be the case for our biologist colleagues? We will know for sure if blackboards in biology departments, like the sand on the book cover, are soon covered in equations!

Nature Cell Biology, August 2009

...a monumental undertaking by three outstanding experts in the field...the book is a rich collection of special topics in biophysics...

Quarterly Review of Biology, September 2009

Physical Biology of the Cell is beautifully crafted: self-contained and modular, it provided tutorials on fundamentals and has material to hold the interest of a more sophisticated reader. It is fast-paced, proceeding within each chapter from freshman basics to graduate level sophistication. The book requires minimal prerequisites: a curious mind and undergraduate calculus will go a long way. It can be used as an undergraduate or early graduate biophysics course in a physics or engineering department. In the context of a molecular cell biology course, it could complement Molecular Biology of the Cell (or its equivalent), serving as a vehicle to introduce biology students to a quantitative way of thinking about biology. To truly master the physics presented in the book, one should do the problems provided with each chapter. These problems are well thought out and are a major teaching resource. (The instructor can also obtain a set of solutions). Because of these features, Physical Biology of the Cell offers a great deal of flexibility as a teaching tool.

Cell, November 2009

About Rob Phillips (California Institute of Technology, USA)

Rob Phillips is in the Department of Applied Physics at the California Institute of Technology. He received a PhD in physics from Washington University in St. Louis. Jane Kondev is in the Department of Physics and the Graduate Program in Quantitative Biology at Brandeis University. He attended the Mathematical High School in Belgrade, Serbia, received his Physics BS degree from the University of Belgrade, and his PhD from Cornell University. Julie Theriot is in the Department of Biochemistry and the Department of Microbiology and Immunology at the Stanford University School of Medicine. She received concurrent BS degrees in Physics and Biology from the Massachusetts Institute of Technology, and a PhD in Cell Biology from the University of California at San Francisco.

Table of Contents

Part I The Facts of Life
1. Why: Biology By the Numbers
2. What and Where: Construction Plans for Cells and Organisms
3. When: Stopwatches at Many Scales
4. Who: Bless the Little Beasties

Part II Life at Rest
5. Mechanical and Chemical Equilibrium in the Living Cell
6. Entropy Rules!
7. Two-State Systems: From Ion Channels to Cooperative Binding
8. Random Walks and the Structure of Macromolecules
9. Electrostatics for Salty Solutions
10. Beam Theory: Architecture for Cells and Skeletons
11. Biological Membranes: Life in Two Dimensions

Part III Life in Motion
12. The Mathematics of Water
13. A Statistical View of Biological Dynamics
14. Life in Crowded and Disordered Environments
15. Rate Equations and Dynamics in the Cell
16. Dynamics of Molecular Motors
17. Biological Electricity and the Hodgkin-Huxley Model

Part IV The Meaning of Life
18. Sequences, Specificity and Evolution
19. Network Organization in Space and Time
20. Whither Physical Biology

Additional information

CIN0815341636G
9780815341635
0815341636
Physical Biology of the Cell by Rob Phillips (California Institute of Technology, USA)
Used - Good
Paperback
Taylor & Francis Inc
20081118
800
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
This is a used book - there is no escaping the fact it has been read by someone else and it will show signs of wear and previous use. Overall we expect it to be in good condition, but if you are not entirely satisfied please get in touch with us

Customer Reviews - Physical Biology of the Cell