It's the dawn of the 22nd century, and the world has fallen apart. The United States has become a nation of migrants - starving masses of nomads who seek out a living in encampments outside government seed-distribution warehouses. In this new world, there is a new power. Satori is more than just a corporation; she is an intelligent, living city that grew out of the ruins of Denver. Satori bioengineers both the climate resistant seed that feeds a hungry nation and her own post-human genetic Designers, Advocates, and Laborers. What remains of the United States government now exists solely to distribute Satori seed; a defeated American military doles out bar-coded, single-use Satori seed to the nation's starving citizens.

When one of Satori's Designers goes rogue, Agent Sienna Doss is tasked with bringing her in: the government wants to use the Designer to break Satori's stranglehold on seed production and reassert themselves as the center of power. As events spin out of control, Sienna finds herself at the heart of Satori, where an explosive climax promises to reshape the future of the world.