The new edition is renamed to reflect the essential information required of the student, primary care practitioner and pharmacist who needs both basic and clinical information to apply therapeutics in the treatment of disease. A new emphasis on the disease-based approach brings it fully in step with ongoing changes in the medical curriculum as it continues its focus on the rationale behind therapeutic decision-making. New features include an overview chapter: practical steps required for optimal therapeutic decisions; newly emerging advances in therapeutics; cost/benefit analysis of therapy; increased coverage of drug interactions; and much more