A rationale for EBMH. Clinical governance. Information needs in everyday clinical practice. Asking clinical questions. Getting answers. Resources. Designing a research project. Case reports, series and uncontrolled studies. Surveys. Clincal audit.Qualitative studies. Case-control studies. Cohort studies. Clinical trials. Economic analysis. Systematic reviews and meta-analysis. Types of data. Rates. Probability. Parametric and non-parametric statistics. Measures of central tendency and dispersion. Camparing groups. Relationships between groups. Multivariate statistics. Meta-analysis statistics. Critical appraisal diagnosis, treatment, systematic reviews and meta-analysis, prognosis, economics, guidelines, aetiology/harm, clinical audit. Mock exam papers.