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A Pharmacology Primer Summary

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery by Terry P. Kenakin, PhD (Professor, Pharmacology, University of North Carolina, USA)

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, 4th Edition features the latest ideas and research about the application of pharmacology to the process of drug discovery to equip readers with a deeper understanding of the complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This edition has been thoroughly revised to include material on data-driven drug discovery, biased signaling, structure-based drug design, drug activity screening, drug development (including pharmacokinetics and safety Pharmacology), and much more. With more color illustrations, examples, and exercises throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery, or pharmacologic research.

A Pharmacology Primer Reviews

"This edition adds solid overviews of emerging topics in the field...which keep it at the cutting edge of receptor pharmacology...a valuable resource for students of pharmacology and all members of drug discovery and design teams. Rating: 4 Stars" --Doody's.com, Sep 2014 "a major strength of the present monograph is the authors long-standing commitment to the didactic promotion of the discipline of pharmacology as the primary, unifying discipline of drug discovery. This monograph remains the key reference work in pharmacology and receptor theory, providing an irreplaceable yet accessible reference source for all scientists involved in biomedical research as it pertains to drug discovery." --Drug Development Research, June 2014 "A wonderful contribution to the world of pharmacology that takes the reader from introductory information to advanced receptor theory. This book will be useful to both students and seasoned researchers alike. Beautifully illustrated and clearly written, this book is a welcome addition to every library." --P Michael Conn, PhD, Senior Vice President for Research and Associate Provost, Professor of Internal Medicine, School of Medicine, Professor of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX

About Terry P. Kenakin, PhD (Professor, Pharmacology, University of North Carolina, USA)

Dr. Terry Kenakin is Professor of Pharmacology at the University of North Carolina School of Medicine. Prior to this, he spent 7 years in drug discovery at Burroughs-Wellcome. He then moved to GlaxoSmithKline for 25 years. Dr. Kenakin has written 11 books on Pharmacology, is the Editor in Chief of the Journal of Receptors and Signal Transduction, is on numerous Editorial Boards. He is the Editor-in-Chief of Comprehensive Pharmacology (Elsevier, 2022). He is the recipient of the 2008 Poulsson Medal for Pharmacology awarded by the Norwegian Society of Pharmacology for achievements in basic and clinical pharmacology and toxicology. He has also been awarded the 2011 Ariens Award from the Dutch Pharmacological Society and the 2014 Gaddum Memorial Award from the British Pharmacological Society, and the 2020 Goodman and Gilman Award in Receptor Pharmacology from ASPET.

Table of Contents

Chapter 1 What is Pharmacology?Chapter 2 How Different Tissues Process Drug ResponseChapter 3 Drug Receptor TheoryChapter 4 Pharmacological Assay Formats: BindingChapter 5 Agonists: The Measurement of Affinity and Efficacy in Functional AssaysChapter 6 Orthosteric Drug AntagonismChapter 7 Allosteric Drug InteractionsChapter 8 Drug DiscoveryChapter 9 Drug Development: Pharmacokinetics and Safety PharmacologyChapter 10 Target-and System-based Strategies for Drug DiscoveryChapter 11 Lead Optimization: Data-Driven AnalysisChapter 12 Statistics and Experimental DesignChapter 13 Selected Pharmacological MethodsChapter 14 Exercises in Pharmacodynamics and PharmacokineticsGlossary of Pharmacological TermsAppendicesStatistical TablesMathematical Fitting Functions

Additional information

GOR007357561
9780124076631
0124076637
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery by Terry P. Kenakin, PhD (Professor, Pharmacology, University of North Carolina, USA)
Used - Very Good
Hardback
Elsevier Science Publishing Co Inc
2014-04-08
450
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
This is a used book - there is no escaping the fact it has been read by someone else and it will show signs of wear and previous use. Overall we expect it to be in very good condition, but if you are not entirely satisfied please get in touch with us

Customer Reviews - A Pharmacology Primer