SECTION I * Introduction
1. The Global Burden ofCardiovascular Diseases
Catherine P. Benziger, Andrew E. Moran,Gregory A. Roth, and George A. Mensah
2.Clinical Cardiovascular Examination
William R. Miranda and Rick A. Nishimura
3.Cardiovascular Imaging Techniques
Thomas H. Marwick and Jagat Narula
4.Genomics and Epigenomics of Heart Diseases
June-Wha Rhee and Joseph C. Wu
SECTIONII * Risk Factors for Cardiovascular Disease
5.Epidemiology, Pathophysiology, and Treatment of Hypertension
Michael E. Hall, John E. Hall, and Paul K.Whelton
6.Cardiometabolic Disease: Insulin Resistance, Obesity, and the MetabolicSyndrome
W. Timothy Garvey and Jeffrey I. Mechanick
7.Diabetes and Cardiovascular Disease
Jeffrey I. Mechanick and Michael E. Farkouh
8.Tobacco-Related Cardiovascular Disease
Nancy A. Rigotti, Sara Kalkhoran, and NealL. Benowitz
9.Air Pollution and Cardiovascular Disease
Michael B. Hadley and Sanjay Rajagopalan
10.Hypercholesterolemia, Hyperlipoprotein(A), Hypertriglyceridemia, and Low HDL
Robert S. Rosenson, Marlys L. Koschinsky,Borge G. Nordestgaard, and Robert A. Hegele
11.Psychological Factors in Cardiovascular Health and Disease
Darwin R. Labarthe and Rosalba Hernandez
12.Sedentary Lifestyle and Role of Exercise in Cardiovascular Diseases
Ambarish Pandey, Nitin Kondamudi, and CarlJ. Lavie
13.Nutrition, Diet, and Alcohol in Health and Cardiovascular Disease
Marta Guasch-Ferre and Frank Hu
14.Inflammation and Atherosclerosis
Hasan K. Siddiqi and Paul M. Ridker
15.Location and Level of Care, Education, Availability of Medicines, andCardiovascular Mortality
Rajeev Gupta, Philip Joseph, AnnikaRosengren, and Salim Yusuf
SECTIONIII * Atherosclerosis and Coronary Heart Disease
16.Pathology and Pathogenesis of Atherosclerosis and its Progression
Jagat Narula, Erling Falk, and ValentinFuster
17.Pathogenesis of Coronary Thrombosis and Myocardial Infarction
Gemma Vilahur, Valentin Fuster, and BorjaIbanez
18.ST-Elevation Myocardial Infarction (STEMI)
Borja Ibanez, Manesh Patel, InesGarcia-Lunar, Usman Baber, Jonathan Halperin, and Valentin Fuster
19.Evaluation and Management of Non-ST-Segment Elevation Acute Coronary Syndromes
Eric R. Bates, David J. Moliterno, andManesh R. Patel
20.Mimickers of Atherosclerotic Myocardial Infarction: SCAD, Coronary Vasospasm,Myocarditis, and Takotsubo Syndrome
Jacqueline Saw, Jaya Chandrasekhar, SarahZaman, and Harmony Reynolds
21.Chronic Coronary Syndromes
Sripal Bangalore, Ziad Ali, Jagat Narula,John Puskas, and Gregg W. Stone
22.Cardiac Rehabilitation: Current Practice and Future Directions
Alan Rozanski, Saman Setareh-Shenas, andJagat Narula
SECTIONIV * Diseases of the Great Vessels and Peripheral Vessels
23.Diseases of the Aorta
John A. Elefteriades, Bulat A. Ziganshin,and Jonathan L. Halperin
24.Carotid Artery Disease
Christopher J. White
25.Cerebrovascular Disease
Hugo J. Aparicio, Vasileios Lioutas, ThanhN. Nguyen, and Sudha Seshadri
26.Diagnosis and Management of Diseases of the Peripheral Arteries
Hillary Johnston-Cox, Daniella Kadian-Dodov,and Jeffrey W. Olin
SECTIONV * Valvular Heart Disease
27.Acute Rheumatic Fever
Liesl Zuhlke, Jagat Narula, Mark Engel, andJonathan R. Carapetis
28.Aortic Stenosis
Marie-Annick Clavel, Marc R. Dweck, Martin Leon,and Philippe Pibarot
29.Aortic Regurgitation, Mixed Valvular Heart Disease, and Heart Valve Prostheses
Patrizio Lancellotti, Alexandra Chitroceanu,Simona Sperlongano, Raluca Dulgheru, and Adriana Postolache
30.Mitral Regurgitation
Jeroen J. Bax, Nina Ajmone Marsan, Pietervan der Bijl, Hendrik Treede, Michele DeBonis, Bernard Prendergast, BernardIung, and Victoria Delgado
31.Acquired Tricuspid Valve Diseases
Luigi P. Badano, Ana Pardo, Denisa Muraru,and Jose Louis Zamorano
32.Mitral Stenosis
Vinay K. Bahl and Ravi S. Math
33.Infective Endocarditis
Ann F. Bolger
SECTIONVI * Rhythm and Conduction Abnormalities
34.Electrophysiologic Anatomy, Mechanisms of Arrhythmias and ConductionDisturbances, and Genetics
Peng-Sheng Chen, MD, Siew Yen Ho, Silvia G.Priori, and Charles Antzelevitch
35.Supraventricular Tachycardia: Atrial Tachycardia, Atrioventricular NodalReentry, and Wolff-Parkinson-White Syndrome
David Spragg and Hugh Calkins
36.Atrial Fibrillation and Atrial Flutter
Anne B. Curtis, Tina Baykaner, and Sanjiv M.Narayan
37.Ventricular Arrhythmias and Sudden Cardiac Death
Justin Hayase, Kalyanam Shivkumar, and JasonS. Bradfield
38.Conduction System Disturbances and Bradyarrhythmias
Pugazhendhi Vijayaraman, Jeffrey Arkles,Jayanthi N. Koneru, and David J. Callans
39.Diagnosis and Management of Syncope
Zachary D. Goldberger, Mohammed Ruzieh, andBlair P. Grubb
SECTIONVII * Heart Failure
40.Classification of Cardiomyopathies
Eloisa Arbustini, Barry J. Maron, NavneetNarula, and Jagat Narula
41.Dilated Cardiomyopathy
Eloisa Arbustini, Alessandro Di Toro,Lorenzo Giuliani, Mario Urtis, G. William Dec, and Jagat Narula
42.Hypertrophic Cardiomyopathy
Massimiliano Lorenzini and Perry M. Elliott
43.Cardiac Amyloidosis
Morie A. Gertz, Jagat Narula, EdgarArgulian, and Sumeet S. Mitter< /span>
44.Restrictive Heart Diseases
Eloisa Arbustini, Alessandro Di Toro,Lorenzo Giuliani, G. William Dec, and Jagat Narula
45.Left Ventricular Noncompaction
Eloisa Arbustini, Alessandra Serio, LorenzoGiuliani, Nupoor Narula, and Alessandro Di Toro
46.Myocarditis
Eloisa Arbustini, Alessandro Di Toro, MarioUrtis, Sean Pinney, and Jagat Narula
47.Obstructive and Nonobstructive Coronary Disease in Heart Failure
Charlotte Lee and G. William Dec
48.Diagnosis and Management of Chronic Heart Failure
Muhammad Shahzeb Khan, Muthiah Vaduganathan,and Javed Butler
49.Diagnosis and Management of Heart Failure With Preserved Ejection Fraction
Joao Pedro Ferreira, Kavita Sharma, andJaved Butler
50.Evaluation and Management of Acute Heart Failure
Kiran Mahmood, Eric J. Velazquez, andAnuradha Lala
51.Peripartum Cardiomyopathy
Uri Elkayam and Jena Pizula
52.Surgical Management of the Severe Heart Failure Patient: Mechanical CirculatorySupport and Heart Transplantation
Adam D. DeVore, Michelle M. Kittleson,Carmelo A. Milano, Jignesh K. Patel, Joseph G. Rogers, and Jon A. Kobashigawa
SECTIONVIII * Diseases of the Pericardium
53.Acute Pericarditis
James W. Lloyd, Sushil Allen Luis, Zi Ye,and Jae K. Oh
54.Percardial Effusion and Tamponade
Darryl J. Burstow, Sushil Allen Luis, GarvanC. Kane, and Jae K. Oh
55.Constrictive Pericarditis
William R. Miranda, Kevin L. Greason, JohnM. Stulak, and Jae K. Oh
SECTIONIX * Cardiopulmonary Disease
56.Diagnosis and Management of Diseases of the Peripheral Venous System
Daniella Kadian-Dodov, Hillary Johnston-Cox,and Jeffrey W. Olin
57.Pulmonary Hypertension
Yogesh N. V. Reddy and Barry A. Borlaug
58.Pulmonary Embolism
Victor F. Tapson
59.Cor Pulmonale: The Heart in Structural Lung Disease
Lewis J. Rubin
60.Sleep-Disordered Breathing
Shahrokh Javaheri , Dirk Pevernagie, and AliJavaheri
SECTIONX * Critical Cardiovascular Care
61.Evolution of Cardiac Critical Care
Venu Menon and Penelope Rampersad
62.Circulatory and Cardiogenic Shock
Gregory Serrao, Benjamin Bier, and UmeshGidwani
63.Sudden Cardiac Death and Resuscitation
Sanjiv M. Narayan and James P. Daubert
64.Postoperative and Postprocedural Care in the Cardiac Intensive Care Unit
Venu Menon
SECTIONXI * Adult Congenital Heart Disease
65.Anatomical and Physiological Classification of Adult Congenital Heart Disease
Jasmine Grewal and Alexander R. Opotowsky
66.Shunt Lesions
Ari M. Cedars, Shelby Kutty, and AshishDoshi
67.Right-Sided Lesions
Konstantinos Dimopoulos and AndrewConstantine
68.Left Heart Obstructive Lesions
Jennifer Cohen, David Ezon, Kenan Stern, andAli N. Zaidi
69.Single Ventricle Post Fontan Palliation: Tricuspid Atresia, Pulmonary Atresia,and Hypoplastic Left Heart Syndrome
Marie-A Chaix and Paul Khairy
70.Complex Cyanotic Congenital Heart Disease: The Mixing Lesions
Rafael Alonso-Gonzalez and DanielleMassarella
71.Psychosocial Profiles in Adult Congenital Heart Disease and Transition toAdulthood
Philip Moons
SECTIONXII * Special Populations and Topics in Cardiovascular Disease
72.Perioperative Evaluation for Noncardiac Surgery
Daniel Alyesh, Prashant Vaishnava, and KimA. Eagle
73.Anesthesia and the Patient with Cardiovascular Disease
David L. Reich, Elvera L. Baron, and Joel A.Kaplan
74.Cardiovascular Disease in Patients With Cancer and Cardiovascular Complicationsof Cancer Therapies
Edward T. H. Yeh
75.Heart Disease in Chronic Kidney Disease
Jared Hooker, Omar Baber, and Usman Baber
76.Rheumatologic Disease and the Cardiovascular System
Emily Carroll and Yousaf Ali
77.Cardiovascular Disease in Patients with HIV
Pravin Manga, Keir McCutcheon, and Nqoba Tsabedse
78. Heart Disease inPregnancy
Dan G. Halpern, Amy Sarma, Katherine E.Economy, and Anne Marie Valente
79.Traumatic Heart Disease
T. Bruce Ferguson, Jr, Austin Rogers, andRobert Allman
80.Women and Ischemic Heart Disease: An Evolution in Knowledge
Leslee J. Shaw, Viviany R. Taqueti, andNanette K. Wenger
81.Race, Ethnicity, Disparities, and Diversity: The Intersection With HeartDisease
Clyde W. Yancy
82.Cardiovascular Disease and Ageing: Cellular and Molecular Mechanisms
Zoltan Ungvari, Dao-Fu Dai, Bela Merkely,and Anna Csiszar
83.Artificial Intelligence and Cardiovascular Care
John S. Rumsfeld, Bobak J. Mortazavi, andHarlan M. Krumholz
84.Cardiovascular Manifestations of COVID-19
Sean P. Pinney, Gennaro Giustino, andJeffrey I. Mechanick
