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Praise for the Series The series which all immunologists need. --THE PHARMACEUTICAL JOURNAL Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions. --SCIENCE Deserves a permanent place in biomedical libraries as an aid in research and in teaching. --JOURNAL OF IMMUNOLOGICAL METHODS A provocative and scholarly review of research. --JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION Provides an extremely valuable source of reference and many stimulating ideas... the main repository of information in a rapidly developing subject. --THE LANCET Provides unrivaled value in both academic and fiscal terms and should be purchased by hard pressed librarians as a major priority to be jealously defended. --JOURNAL OF MEDICAL MICROBIOLOGY A very valuable serial publication... no serious student of immunology can afford to be without it. --ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

H.-R. Rodewald, Molecular and Cellular Events in Early Thymocyte Development. F. Alt and J.R. Gorman, Regulation of Ig Light Chain Isotype Expression. N. Isakov, The Role of Immunoreceptor Tyrosine-based Activation Motif (ITAM) in Signal Transduction from Antigen and Fc Receptors. G.J. Arlaud, Y. Xu, J.E. Volanakis, V. Rossi, N.M. Thielens, and S.V.L. Narayana, The Atypical Serine Proteases of the Complement System. R. Tripathi, N. Mathieu, I. Leduc, W.M. Hempel, and P. Ferrier, Accessibility Control of V(D)J Recombination: Lessons from Gene Targeting. J.S. Bromberg, L. Qin, and L.A. DeBruyne, Interactions Between the Immune System and Gene Therapy Vectors: Bidirectional Regulation of Response and Expression. D. Penn and W. Potts, MHC Genes Influence Individual Odors and Mating Preferences. A. Chess, Olfactory Receptor Gene Regulation. Subject Index.