Drug Metabolism in Diseases by Wen Xie (Professor of Pharmaceutical Sciences and Pharmacology, The Joseph Koslow Endowed Chair in Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA Director of the Center for Pharmacogenetics, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA)
Drug Metabolism in Diseases is a comprehensive reference devoted to the current state of research on the impact of various disease states on drug metabolism. The book contains valuable insights into mechanistic effects and examples of how to accurately predict drug metabolism during these different pathophysiological states. Each chapter clearly presents the effects of changes in drug metabolism and drug transporters on pharmacokinetics and disposition. This is a unique and useful approach for all those involved in drug discovery and development, and for clinicians and researchers in drug metabolism, pharmacology, and clinical pharmacology.