In a world where monsters called Yoma prey on humans and live among them in disguise, humanity's only hope is a new breed of warrior known as Claymores.

Seven years have passed since the devastating battle in Pieta, and now a new generation of Claymores carries on the fight against the Awakened Ones. However, the mystery of Claire's fate, and of that of her comrades, resurfaces after a surprising discovery made by a young Claymore.